Publications

June 2023
Mocravimod improves overall survival in AML patients undergoing allogeneic hematopoietic cell transplantation
Medinger et al.

April 2023
Mocravimod ameliorates chronic graft-versus-host disease after mouse allogeneic HCT
Zhang et al.

April 2023
Mocravimod, a S1P receptor modulator, increases T cell counts in bone marrow biopsies from patients undergoing allogeneic hematopoietic stem cell transplantation
Dertschnig et al.

January 2023
Mocravimod, a selective sphingosine-1-phosphate receptor modulator, in allogeneic hematopoietic cell transplantation for malignancy
Dertschnig et al.

November 2022
Mocravimod, a s1P receptor agonist, increases both T cell counts in bone marrow biopsies from patients undergoing allogeneic HCT and acute GVHD-freedopm probability
Medinger et al.

June 2022
A two-part, single- and two-arm randomized, open-label study to evaluate the safety, tolerability and pharmacokinetics of KRP203 in subjects with hematological malignancies undergoing allogeneic hematopoietic cell transplantation
Dertschnig et al.

April 2022
A two-part, single- and two-arm randomized, open-label study to evaluate the safety, tolerability and pharmacokinetics and efficacy of KRP203 in subjects undergoing allogeneic hematopoietic cell transplantation for hematological malignancies
Dertschnig et al.

August 2021
A multicentre, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy, safety, and tolerability of the S1P receptor agonist KRP203 in patients with moderately active refractory ulcerative colitis
Radeke et al.

June 2021
S1P Receptor-1 agnoist averts the de novo generation of autoreactive T cells in murine acute GVHD
Vollmer et al.

November 2019
Short-term KRP203 and posttransplant cyclophosmphamide for graft-versus-host disease prophylaxis
Yokoyama et al.

March 2019
GVHD prophylaxis with KRP203, a sphingosine-1-phosphate receptor modulator, is safe and may have the potential to improve survival in patients undergoing allogeneic stem cell transplantation
Heim et al.

February 2018
The role of S1PR1 agonism in thymus-dependent generation of autoreactive T cells during experimental acute Graft-vs-host disease
Vollmer et al.

February 2018
The role of S1PR1 agonism in thymus-dependent T-cell regeneration and Graft-vs-tumor activity following experimental allogeneic hematopoietic cell transplantation
Vollmer et al.

September 2017
Sphingosine 1-phosphate signaling and its pharmacological modulation in allogeneic hematopoietic stem cell transplantation
Smith et al.