Pursuing More Time For Life

Extending and enhancing the quality of life and radically transforming the treatment of patients with hematological malignancies

Pursuing More Time For Life

Extending and enhancing the quality of life and radically transforming the treatment of patients with hematological malignancies

Pursuing More Time For Life

Extending and enhancing the quality of life and radically transforming the treatment of patients with hematological malignancies

At Priothera, our vision is to extend and enhance the quality of life and radically transform the treatment of patients with hematological malignancies.

We are committed to pioneering innovative therapies that can enhance the curative potential of both allogeneic hematopoietic cell transplantation (allo-HCT) and CAR T cell therapy. Our goal is to deliver treatments that not only improve survival rates but also ensure safer and more effective long-term outcomes compared to today’s standard care.

hematologic malignancies

The Impact of Acute Myeloid Leukemia

*From the American Cancer Society 2020

New estimated cases of leukemia (all kinds) in the US

New estimated cases of AML in the US

Estimated deaths from AML in the US

Priothera is exploring ways to address unmet medical needs in hematological malignancies by investigating innovative immune modulators that can enhance outcomes in allogeneic hematopoietic cell transplantation.

Through the development of our investigational drug, mocravimod, we aim to address critical challenges in current allo-HCT maintenance strategies by enhancing the graft-versus-leukemia (GvL) effect while simultaneously reducing graft-versus-host disease (GvHD). 

Science

Hematopoietic Cell Transplantation (HCT)

Mocravimod

Our Pipeline

CAR T Cell Therapy

MO-TRANS Study

Leadership Statement

Florent Gros

Florent Gros,
Founder, CEO of Priothera

“Applying mocravimod’s well-described mode of action to hematological malignancies will bring a game changing treatment to patients suffering from devastating blood cancers.”

Dhaval Patel

Dhaval Patel,
Director, Former EU Research Head, Novartis

“Mocravimod is an outstanding, well-characterized and well-behaved S1P receptor modulator that is well-suited for clinical development and commercial manufacturing. Mocravimod has the potential to be a best-in-class therapy to ameliorate the morbidity and mortality associated with HCT in AML.”
Stephan Oehen

Stephan Oehen,
COO & Founder

“As a non-immunosuppressive small molecule, it decouples the beneficial effects of graft-versus-leukemia (GvL) from the devastating side effects of graft-versus-host disease (GvHD). We have multiple lines of strong pre-clinical and clinical evidence showing that indeed mocravimod offers a unique opportunity to improve survival and quality of life of patients suffering from hematological malignancies.”